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Good morning, investor! We’re starting the last day of this short holiday week with a dive into the biggest pre-market stock movers for Wednesday!

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News moving shares today include earnings reports, clinical trial data, short-squeezes, and more.

Let’s get into that news below!

Pre-Market Stock Movers: 10 Top Gainers

1. Inspira Technologies Oxy (NASDAQ:IINN) stock is soaring more than 42% .
2. Engine Gaming And Media (NASDAQ:GAME) shares are gaining over 33% .
3. Pasithea Therapeutics (NASDAQ:KTTA) stock is surging more than 31%, continuing a nasal spray rally from Tuesday.
4. Ocuphire Pharma (NASDAQ:OCUP) shares are climbing over 30%, .
5. Society Pass (NASDAQ:SOPA) stock is increasing more than 26% .
6. Biolase (NASDAQ:BIOL) shares are rising almost 26% .
7. Synlogic (NASDAQ:SYBX) stock is sitting over 14% higher .
8. Pure Storage (NYSE:PSTG) shares are getting a more than 13% .
9. Spark Networks (NYSEAMERICAN:LOV) stock is jumping over 12% on no news which could be caused by .
10. Longeveron (NASDAQ:LGVN) shares are up more than 9% .

10 Top Losers

1. Nordstrom (NYSE:JWN) stock is plummeting over 27% .
2. Vallon Pharmaceuticals (NASDAQ:VLON) shares are diving more than 27% following a rally on Tuesday.
3. Petros Pharmaceuticals (NASDAQ:PTPI) stock is taking an over 22% beating as it retreats after a rally yesterday.
4. Gap (NYSE:GPS) shares are decreasing more than 20% .
5. Outlook Therapeutics (NASDAQ:OTLK) stock is heading over 20% lower .
6. iSpecimen (NASDAQ:ISPC) shares are pulling back more than 19% after rallying for a couple of days on Covid-19 news.
7. Qualigen Therapeutics (NASDAQ:QLGN) stock is declining close to 18% after running higher on Tuesday.
8. Anaplan (NYSE:PLAN) shares are slipping nearly 18% .
9. Aptevo Therapeutics (NASDAQ:APVO) stock is dropping over 15% .
10. Esperion Therapeutics (NASDAQ:ESPR) shares close out our pre-market stock movers down over 14% following an unexpected surge close to yesterday’s closing bell.

On the date of publication, William White did not have (either directly or indirectly) any positions in the securities mentioned in this article. The opinions expressed in this article are those of the writer, subject to the InvestorPlace.com Publishing Guidelines.